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Stilbene functionalized PEGylated nanoparticles of chitosan/silica

by IPR Cell


The present invention relates to stilbene derivative preferably florbetaben analog conjugated azido-functionalized nanoparticles of chitosan/silica for targeted drug delivery across blood brain barrier. The nanoparticle surface is modified with polyethylene glycol to enhance the plasma residence time by preventing their capture by the reticuloendothelial system.



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